Kwak Min-Seok | Academia pays attention to research on dynamic DNA-based biomaterials | |||
작성자 | 대외협력과 | 작성일 | 2021-07-16 |
조회수 | 675 |
Kwak Min-Seok | Academia pays attention to research on dynamic DNA-based biomaterials | |||||
대외협력과 | 2021-07-16 | 675 |
Academia pays attention to research on dynamic DNA-based biomaterials
Professor Kwak Min-Seok
The thesis of Prof. Kwak Min-Seok (Dept of Chemistry and Industry 4.0 Convergence Bionics Engineering) at Pukyong National University has been published on the cover of Materials Today, an international journal in materials engineering. Materials Today is a world authority on academic journals with an Impact factor (IF) of 26.416, which ranks in the top 2.8% of the journal ranking index (JCR).
Professor Kwak published his thesis 'Dynamic DNA-based biomaterials interacting with external, macroscopic, and molecular stimuli' in the latest issue of the journal. His thesis has been recognized by academia for its outstanding research achievements as a general thesis covering research on dynamic DNA-based biomaterials, introducing basic principles related to medicine and science, and reviews on recent developments in the field. In this paper, Professor Kwak suggested that nucleic acids enzymes compounded by chemical reactions, such as oligonucleotides (oligo), can be mass-produced and can be applied by freely changing the chemical structure and giving new physical properties. As an example, he presented fluorescent DNA and primers, which are essential raw materials for the COVID-19 diagnostic kit. Subsequently, he observed that substances such as oligonucleotides are programmed by nucleic sequence and dynamically interact in response to various stimuli, such as chemical and enzymatic reactions, systemic pH and temperature, complementary sequence and nucleic acid fuel, ligand-receptor and RNA aptamer, and external energy (light and magnetic fields). "I expect that the results of this research, conducted in collaboration with researchers in Germany and China, will provide a vast source of comprehensive information to researchers in related fields," professor Kwak said. Professor Kwak specializes in DNA synthesis and materials science and is actively researching DNA-based gene therapy for cancer, infectious diseases, and immunotherapy.
연구진
곽민석 mkwak@pukyong.ac.kr
자연과학대학 나노화학혼성재료연구실