연구/산학
PKNU Research 1000
| Jung Won-Kyo | Research on Anti-Cancer and Anti-Bacterial Properties of Phytonutrients Gains | |||
| 작성자 | 대외홍보센터 | 작성일 | 2025-02-18 |
| 조회수 | 181 | ||
| Jung Won-Kyo | Research on Anti-Cancer and Anti-Bacterial Properties of Phytonutrients Gains | |||||
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대외홍보센터 |  |
2025-02-18 |  |
181 |
Pukyong National University Key Research Institute’s Research on Anti-Cancer and Anti-Bacterial Properties of Seaweed Gains ‘Attention’
-Synthesis of Functional Silver Nanoparticles Using Phytonutrient-Derived Substances Published in International Journal
The research team from the Marine Bionics Convergence Technology Center (Director Jung Won-Kyo), a key research institute of Pukyong National University, has gained attention for synthesizing silver nanoparticles (AgNPs) using seaweed-derived substances and demonstrating their anti-cancer and anti-bacterial properties.
The team used phlorotannin, a polyphenolic compound isolated from brown algae species, and synthesized functional silver nanoparticles (AgNPs). They presented the results of the synthesis mechanism through optimized synthesis processes, anti-cancer and anti-bacterial activity evaluations, and molecular dynamics simulations.
The silver nanoparticles successfully synthesized through the optimized process exhibited excellent anti-cancer and anti-bacterial effects in the experiments conducted by the research team. The team also performed molecular dynamics simulations to predict the phlorotannin and silver nanoparticle synthesis process at the molecular level, identifying the nanoparticle formation process and pH-dependent molecular behaviors.
The research team included the first author, Ph.D. candidate Kim Nam-gyun (Department of Industry 4.0 Convergence Bionics Engineering), corresponding author Professor Jung Won-Kyo (Department of Biomedical Engineering), co-author Professor Yi Myunggi (Department of Biomedical Engineering), student Lee Hye-won (4th-year Biomedical Engineering), Master’s student Hadi Sedigh Malekroodi (Department of Industry 4.0 Convergence Bionics Engineering), Professor Kim Young-Mog (Department of Food Engineering), and postdoctoral researcher Oh Do Kyung (Department of Food Engineering), all contributing to the successful collaborative interdisciplinary research.
The research paper titled ‘Harnessing marine-derived polyphenols for the one-pot synthesis of functional silver nanoparticles: Anti-cancer, anti-bacterial, and MD simulation’ was published in the prestigious international journal <Nano Today> (IF 13.2, JCR ranking TOP 7.6%) in the field of materials science.
Through this research, the team has gathered essential data for the development of advanced bio-medical materials using marine natural products and has provided key technologies for the synthesis of natural product-based nanomaterials, expecting to overcome existing technological limitations.
This research was supported by the National Research Foundation of Korea’s University Key Research Institute Program and the Doctoral Research Incentive Program (Research Leader: Kim Nam-gyun).
